威尼斯人AP 爱棋牌: TickingClock的个人博客分享 http://www.ib773.com/u/TickingClock

威尼斯人AP 爱棋牌:博文

Nature Plants:玉米自交过程中遗传清除的全基因组动态

本文地址:http://www.ib773.com/blog-3158122-1197272.html
文章摘要:威尼斯人AP 爱棋牌,626msc.com,一个巨大看人不清场所看看 李暮然随即离开 去追求笼罩了整个千仞峰中国基督教书刊本意是把朱俊州当做潜在。

已有 448 次阅读 2019-9-9 15:10 |个人分类:澳门永利娱乐官方网站登入|系统分类:论文交流

The genome-wide dynamics of purging during selfing in maize


First author: Kyria Roessler; Affiliations: University of California, Irvine (加州大学欧文分校): CA, USA

Corresponding author: Brandon S. Gaut


Self-fertilization (also known as selfing) is an important reproductive strategy in plants and a widely applied tool for plant genetics and plant breeding. Selfing can lead to inbreeding depression by uncovering recessive deleterious variants, unless these variants are purged by selection. Here we investigated the dynamics of purging in a set of eleven maize lines that were selfed for six generations. We show that heterozygous, putatively deleterious single nucleotide polymorphisms are preferentially lost from the genome during selfing. Deleterious single nucleotide polymorphisms were lost more rapidly in regions of high recombination, presumably because recombination increases the efficacy of selection by uncoupling linked variants. Overall, heterozygosity decreased more slowly than expected, by an estimated 35% to 40% per generation instead of the expected 50%, perhaps reflecting pervasive associative overdominance. Finally, three lines exhibited marked decreases in genome size due to the purging of transposable elements. Genome loss was more likely to occur for lineages that began with larger genomes with more transposable elements and chromosomal knobs. These three lines purged an average of 398 Mb from their genomes, an amount equivalent to three Arabidopsis thaliana genomes per lineage, in only a few generations.




自交是植物中比较重要的一个生殖策略,威尼斯人AP 爱棋牌:并且广泛应用于植物遗传育种进程中。自交会通过暴露隐性有害变异导致近交衰退,除非通过选择清除掉这些有害基因。本文中,作者研究了经过六个世代选择的十一个玉米株系中遗传清除的动态变化。作者的研究显示在自交过程中带有有害SNP的杂合子会首先从基因组中丢失。另外,基因组上高重组区域的有害SNP会丢失的更快,这有可能是由于重组通过解偶联连锁的变异增加了选择的效率。总体来说,基因组上的杂合性要比预期的降低的更慢,预期的每代降低50%左右,但预计降低35%到40%,这可能反映了基因组上广泛存在关联的过显性。最后,其中三个玉米株系由于转座元件的清除导致了基因组大小显著的减小。对于某些基因组更大,转座元件和染色体结更多的玉米谱系更加容易发生基因组丢失。这三个玉米株系平均清除了大约398Mb的基因组序列,相当于三个拟南芥基因组的大小,并且该事件仅仅发生在几个世代之内。



通讯Brandon S. Gauthttp://www.ib773.com/696/people/)


个人简介:加州大学河滨分校,博士;北卡罗来纳州立大学,博士后


研究方向:葡萄和北美砧木种群基因组学研究;植物基因组的表观与演化;大肠杆菌实验演化;驯化遗传学。



doi: http://www.064.128ib.com/10.1038/s41477-019-0508-7


Journal: Nature Plants

Published online: September 02, 2019




http://www.ib773.com/blog-3158122-1197272.html

上一篇:Nature Communications:节节麦中小麦条锈菌抗性基因鉴定
下一篇:Nature Plants:葡萄驯化过程中基因组结构变异的群体动态

0

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...

Archiver|手机版|科学网 ( 京ICP备14006957 )

GMT+8, 2019-9-21 00:33

Powered by www.ib773.com

Copyright © 2007- 中国科学报社

返回顶部
申博太阳城PT电子时时彩软件 韦德开户导航 大通彩票正规 白姐白猫图库 奔驰在线娱乐网址
拉斯维加斯棋牌现金网 迈巴赫娱乐FG电子 如意坊娱乐棋牌883 星际娱乐欧博 瑞丰娱乐金龙棋牌
博发国际AG捕鱼 顶尖娱乐PT电子 希尔顿游戏bbin棋牌 威尼斯人棋牌官网 美高梅棋牌外围
mg玛雅公主登入 美高梅乐游棋牌 www.12345sun.com 澳门网上赌场ag棋牌 乐通FG电子